Kovochich M., Oh SC, Ferrari BJD, Masset T, Breider F, Unice K. (2025). Characterization of tire and road wear particles in experimental biota samples. Scientific Reports, 15(1):15372. doi: 10.1038/s41598-025-98902-3.

Kougias, D.G., Southall, M. D., Scialli, A., Atillasoy, E., Schaeffer, T., Ejaz, S., Chu, C., Jeminiwa, B. O., Massarsky, A.,  Unice, K., Kovochich, M. (2025). A Quantitative Weight-of-Evidence Review of Preclinical Studies Examining the Potential Developmental and Reproductive Toxicity of Acetaminophen. Critical Reviews in Toxicology. doi: 10.1080/10408444.2024.2446471.

Kougias, D.G., Atillasoy, E., Southall, M. D., Scialli, A., Jeminiwa, B. O., Massarsky, A.,  Unice, K., Schaeffer, T., Ejaz, S., Chu, C., Kovochich, M. (2025). A Quantitative Weight-of-Evidence Review of Preclinical Studies Examining the Potential Developmental Neurotoxicity of Acetaminophen. Critical Reviews in Toxicology. doi: 10.1080/10408444.2024.2442344.

Jacobs, N., Kougias, D.G., Louie, F., Roberts, B. (2024). A screening-level human health risk assessment of dietary intake of pesticide residues in produce as compared to consumer guide recommendations. Critical Reviews in Toxicology, 54(4): 214-234. doi: 10.1080/10408444.2024.2316136.

Kovochich, M., Oh, S. C., Lee J. P., Parker, J. A., Barber, T., Unice, K. (2023) Characterization of tire and road wear particles in urban river samples. Environmental Advances, 12. doi: 10.1016/j.envadv.2023.100385.

Kovochich, M., Parker, J. A., Oh, S. C., Lee J. P., Wagner, S., Reemtsma, T., Unice, K. (2021) Characterization of Individual Tire and Road Wear Particles in Environmental Road Dust, Tunnel Dust, and Sediment. Environmental Science & Technology Letters, 8(12), 1057-1064. doi: 10.1021/acs.estlett.1c00811.

Eichenbaum, G., Wilsey, J.T., Fessel, G., Qiu, Q.Q., Perkins, L., Hasgall, P., Monnot, A., More, S.L., Egnot, N., Sague, J., Marcello, S., Connor, K., Scutti, J., Christian, W.V., Coplan, P.M., Wright, J., Hastings, B., Katz, L.B., Vreeke, M., Calistri-Yeh, M., Faiola, B., Purushothaman, B., Nevelos, J., Bashiri, M., Christensen, J.B., Kovochich, M., Unice, K. (2021) An integrated benefit-risk assessment of cobalt-containing alloys used in medical devices: Implications for regulatory requirements in the European Union. Regulatory Toxicology and Pharmacology, 125. doi: 10.1016/j.yrtph.2021.105004.

Kovochich, M., Liong, M., Parker, J.A., Oh, S.C., Lee, J.P., Xi, L., Kreider, M.L., & Unice, K.M. (2021). Chemical mapping of tire and road wear particles for single particle analysis. Science of the Total Environment, 757:144085. doi: 10.1016/j.scitotenv.2020.144085.

Kirkland, D., Kovochich, M., More, S., Murray, F.J., Monnot, A.D., Miller, J., Jaeschke, H., Jacobson-Kram, D., Deore, M., Pitchaiyan, S.K., Unice, K., Eichenbaum, G. (2021). A comprehensive weight of evidence assessment of published acetaminophen genotoxicity data: Implications for its carcinogenic hazard potential. Regulatory Toxicology and Pharmacology, 122: 104892. doi: 10.1016/j.yrtph.2021.104892.

More S.L., Kovochich, M., Lyons-Darden, T., Taylor, M., Schulte, A.M., Madl, A.K. (2021). Review and evaluation of the potential health effects of oxidic nickel nanoparticles. Nanomaterials, 11(3):642. doi: 10.3390/nano11030642.

Monnot A.D, Kovochich, M., Bandara, S.B., Wilsey, J.T., Christian, W.V., Eichenbaum, G., Perkins, L.E.L., Hasgall, P., Taneja, M., Connor, K., Sague, J., Nasseri-Aghbosh, B., Marcello, S., Vreeke, M., Katz, L.B., Reverdy, E.E., Thelen, H., Unice, K. (2021). A hazard evaluation of the reproductive/developmental toxicity of cobalt in medical devices. Regulatory Toxicology and Pharmacology, 123:104932. doi: 10.1016/j.yrtph.2021.104932.

Kovochich, M., Monnot, A., Kougias, D. G., More, S. L., Wilsey, J. T., Qiu, Q-Q., Perkins, L. E. L., Hasgall, P., Taneja, M., Reverdy, E. E., Sague, J., Marcello, S., Connor, K., Scutti, J., Christian, W. V., Coplan, P., Katz, L. B., Vreeke, M., Calistri-Yeh, M., Faiola, B., Unice, K., Eichenbaum, G. (2021). Carcinogenic hazard assessment of cobalt-containing alloys in medical devices: Review of in vivo studies. Regulatory Toxicology and Pharmacology, 122: 104910. doi: 10.1016/j.yrtph.2021.104910.

Murray, J., Monnot, A., Jacobson-Kram, D., Cohen, S.M., Hardisty, J., Bandara, S., Kovochich, M., Deore, M., Pitchaiyan, S., Gelotte, C., Lai, J.C.K., Atillasoy, E., Hermanowski-Vosatka, A., Kuffner, E., Unice, K., Yang, K., Gebremichael, Y., Howell, B.A., Eichenbaum, G. (2020). A critical review of the acetaminophen pre-clinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential. Regulatory Toxicology and Pharmacology, 118:104801. doi: 10.1016/j.yrtph.2020.104801.

Unice, K.M., Kovochich, M., Monnot, A.D. Cobalt-containing dust exposures: Prediction of whole blood concentrations using a biokinetic model. (2020). Science of the Total Environment, 723:137968. doi: 10.1016/j.scitotenv.2020.137968.

Kougias, D.G., Miller, E., McEwen, A., Reamer, H., Kovochich, M., Pierce, J. (2020). Risk assessment of glyphosate exposures from pilot study with simulated heavy residential consumer application of Roundup® using a Margin of Safety (MOS) approach. Risk Analysis, 41(9): 1693-1715. doi: 10.1111/risa.13646.

Pierce, J.S., Roberts, B., Kougias, D.G., Comerford, C.E., Riordan, A.S., Keeton, K.A., Reamer, H.A., Jacobs, N.F.B., Lotter, J.T. (2020). Pilot study evaluating inhalation and dermal glyphosate exposure resulting from simulated heavy residential consumer application of Roundup®. Inhalation Toxicology, 32(8): 354-367. doi: 10.1080/08958378.2020.1814457.

Lewis Jr., N. A., Kougias, D. G., & Takahashi, K. J., Earl, A. (2020). The Behavior of Same-Race Others and Its Effects on Black Patients’ Attention to Publicly Presented HIV-Prevention Information. Health Communication, 36(10): 1252-9. doi: 10.1080/10410236.2020.1749369.

Sellinger, E. P., Kougias, D. G., Drzewiecki, C. M., Juraska, J. M. (2020). Behavioral effects in adult rats exposed to low doses of a phthalate mixture during the perinatal or adolescent period. Neurotoxicology and Teratology, 79: 106886. doi: 10.1016/j.ntt.2020.106886.

Kougias, D. G. (2020). Letter to the editor re: “Herbicide biomonitoring in agricultural workers in Valle del Mayo, Sonora Mexico” by Balderrama-Carmona et al. (2019) in Environ Sci Pollut Res Int (https://doi.org/10.1007/s11356-019-07087-6). Environmental Science and Pollution Research, 27(14): 17429-17433. doi: 10.1007/s11356-020-08388-x. Full online-only access: https://rdcu.be/b3dLn.

Kovochich, M., Finley, B.L., Novick, R., Monnot, A.D., Donovan, E., Unice, K.M., Fung, E.S., Fung, D., Paustenbach, D.J. Understanding Outcomes and toxicological aspects of second-generation metal-on-metal hip implants: A state-of-the-art review. (2019). Critical Reviews in Toxicology, 48(10): 839. doi: 10.1080/10408444.2018.1563048.

Moody, L., Hernandez-Saavedra, D., Kougias, D. G., Chen, H., Juraska, J. M., Pan, Y-X. (2019). Tissue-specific changes in Srebf1 and Srebf2 expression and DNA methylation with perinatal phthalate exposure. Environmental Epigenetics, 5(2): dvz009. doi: 10.1093/eep/dvz009.

Fung, E.S., Unice, K.M., Paustenbach, D.J., Finley, B.L., Kovochich, M. (2018). Methods for sterilizing clinically-relevant wear particles isolated from metal-on-metal hip implants. Scientific Reports, 8(1):2384. doi: 10.1038/s41598-017-18239-4.

Moody, L., Kougias, D., Jung, P., Digan, I., Hong, A., Gorski, A., Chen, H., Juraska, J., M. Pan, Y-X. (2018). Perinatal phthalate and high-fat diet exposure induce sex-specific changes in adipocyte size and DNA methylation. The Journal of Nutritional Biochemistry, 65: 15-25. doi: 10.1016/j.jnutbio.2018.11.005.

Kougias, D. G., Sellinger, E. Willing, J., Juraska, J. M. (2018). Perinatal exposure to an environmentally relevant mixture of phthalates results in a lower number of neurons and synapses in the medial prefrontal cortex and decreased cognitive flexibility in adult male and female rats. The Journal of Neuroscience, 38(31):6864-6872. doi: 10.1523/JNEUROSCI.0607-18.2018.

Kougias, D. G., Tapas, D., Perez, A. B., Pereira, S. (2018). A role for nutritional intervention in addressing the aging neuromuscular junction. Nutrition Research, 53:1-14. doi: 10.1016/j.nutres.2018.02.006.

Kougias, D. G., Cortes, Moody, L., L. Rhoads, S. G., Pan, Y., Juraska, J. M. (2018). Effects of Perinatal Exposure to Phthalates and a High-Fat Diet on Maternal Behavior and Pup Development and Social Play. Endocrinology. 159 (2):1088-1105. doi: 10.1210/en.2017-03047.

Kovochich, M., Fung, E.S., Donovan, E., Unice, K.M., Paustenbach, D.J., Finley, B.L. (2017). Characterization of wear debris from metal‐on‐metal hip implants during normal wear versus edge‐loading conditions. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 106(3): 986. doi: 10.1002/jbm.b.33902.

Fung, E.S., Monnot, A., Kovochich, M., Unice, K.M., Tvermoes, B.E., Galbraith, D., Finley, B.L., Paustenbach, D.J. (2017). Characteristics of cobalt-related cardiomyopathy in metal hip implant patients: An evaluation of 15 published reports. Cardiovascular Toxicology, 18: 206. doi: 10.1007/s12012-017-9433-z.

Kovochich, M., Fung, C.D., Avanasi, R., Madl, A.K. (2017). Review of techniques and studies characterizing the release of carbon nanotubes from nanocomposites: Implications for exposure and human health risk assessment. Journal of Exposure Science & Environmental Epidemiology, 28: 203. doi: 10.1038/jes.2017.6.

Kougias, D. G., Hankosky, E. R., Gulley, J. M., Juraska, J. M. (2017). Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates age-related deficits in water maze performance, especially in male rats. Physiology & Behavior, 170:93-99. doi: 10.1016/j.physbeh.2016.12.025.

Hankosky, E. R., Sherrill, L. K., Ruvola, L. A., Haake, R. M., Kim, T., Hammerslag, L. R., Kougias, D. G., Juraska, J. M., Gulley, J. M. (2017). Effects of β-hydroxy-β-methyl butyrate (HMB) on working memory and cognitive flexibility in an animal model of aging. Nutritional Neuroscience, 20(7):379-387. doi: 10.1080/1028415X.2016.1145376.

Kougias, D. G., Nolan, S. O., Koss, W. A., Kim, T, Hankosky, E. R., Gulley, J. M., Juraska, J. J. (2016). Beta-hydroxy-beta-methylbutyrate (HMB) ameliorates aging effects in the dendritic tree of pyramidal neurons in the medial prefrontal cortex of both male and female rats. Neurobiol Aging. 40:78-85. doi: 10.1016/j.neurobiolaging.2016.01.004.

Winans, B., Tvermoes, B.E., Unice, K.M., Kovochich, M., Fung, E.S., Christian, W.V., Donovan, E., Finley, B.L., Kimber, I., Paustenbach, D.J. (2016). Data on the histological and immune cell response in the popliteal lymph node in mice following exposure to metal particles and ions. Data in Brief, 9: 388-397. doi: 10.1016/j.dib.2016.08.037.

Tvermoes, B.E., Unice, K.M., Winans, B., Kovochich, M., Christian, W.V., Donovan, E., Fung, E.S., Finley, B.L., Kimber, I. Paustenbach, D.J. (2016). A preliminary evaluation of immune stimulation following exposure to metal particles and ions using the mouse popliteal lymph node assay. Toxicology and applied pharmacology, 308: 77-90. doi: 10.1016/j.taap.2016.07.020.

Madl, A.K., Liong, M., Kovochich, M., Finley, B.L., Paustenbach, D.J., Oberdörster, G. (2015). Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part I: Physicochemical properties in patient studies and simulators. Nanomedicine: Nanotechnology, Biology, and Medicine, 11(5):1201–1215. doi: 10.1016/j.nano.2014.12.005.

Madl, A.K., Kovochich, M., Liong, M., Finley, B.L., Paustenbach, D.J., Oberdörster, G. (2015). Toxicology of wear particles of cobalt-chromium alloy metal-on-metal hip implants Part II: Importance of physicochemical properties and dose in animal and in vitro studies as a basis for risk assessment. Nanomedicine: Nanotechnology, Biology, and Medicine, 11(5):1285–1298. doi: 10.1016/j.nano.2015.02.006.

Cowan, D.M., Kingsbury, T., Perez, A., Woods, T.A., Kovochich, M., Hill, D., Madl, A.K., Paustenbach, D.J. (2014). Evaluation of the California Safer Consumer Products Regulation and the impact on consumers and product manufacturers. Regulatory Toxicology and Pharmacology, 68(1):23-40. doi: 10.1016/j.yrtph.2013.11.001.

Kovochich, M., Avanasi, R., Madl, A.K. (2013). Analysis of factors associated with the releasability of carbon nanotubes (CNTs) from materials containing nanocomposites. TechConnect World Conference, 3:485-488.

Madl, A.K, Unice, K., Kreider, M., Kovochich, M., Bebenek, I.G., Abramson, M.M. (2013). Risk ranking framework to assess the health hazard of nanomaterial containing products in an industrial and consumer application setting. TechConnect World Conference, 3:477-480.

Marsden, M.D., Kovochich, M., Suree, N., Shimizu, S., Mehta, R., Cortado, R., Bristol, G., An, D.S., Zack, J.A. (2012). HIV latency in the humanized BLT mouse. Journal of Virology, 86(1): 339-47. doi: 10.1128/jvi.06366-11.

Kovochich, M., Marsden, M.D., Zac, J.A. (2011). Activation of latent HIV using drug-loaded nanoparticles. PLoS One, 6(4): e18270. doi: 10.1371/journal.pone.0018270.

Kovochich, M., Espinasse, B., Auffan, M., Hotze, E.M., Wessel, L., Xia, T., Nel, A.E., Wiesner, M.R. (2009). Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition. Environmental Science & Technology, 43(16): 6378-84. doi: 10.1021/es900990d.

Xia, T., Kovochich, M., Liong, M., Meng, H., Kabehie, S., George, S., Zink, J.I., Nel, A.E. (2009). Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. ACS Nano, 3(10): 3273-86. doi: 10.1021/nn900918w.

Xia, T., Kovochich, M., Liong, M., Madler, L., Gilbert, B., Shi, H., Yeh, J.I., Zink, J.I., Nel, A.E. (2008). Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano, 2(10): 2121-2134. doi: 10.1021/nn800511k.

Liong, M., Lu, J., Kovochich, M., Xia, T., Ruehm, S.G., Nel, A.E., Tamanoi, F., Zink, J.I. (2008). Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. ACS Nano, 2(5):889-896. doi: 10.1021/nn800072t.

Xia, T., Kovochich, M., Liong, M., Zink, J.I., Nel, A.E. (2008). Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano, 2(1): 85-96. doi: 10.1021/nn700256c.

Lu, J., Liong, M., Sherman, S., Xia, T., Kovochich, M., Nel, A.E., Zink, J.I., Tamanoi, F. (2007). Mesoporous silica nanoparticles for cancer therapy: Energy-dependent cellular uptake and delivery of paclitaxel to cancer cells. Nanobiotechnology, 3(2): 89-95. doi: 10.1007/s12030-008-9003-3.

Xia, T., Kovochich, M., Nel, A.E. (2007). Impairment of mitochondrial function by particulate matter (PM) and their toxic components: Implications for PM-induced cardiovascular disease. Frontiers in Bioscience, 12: 1238-46. doi: 10.2741/2142.

Xia, T., Kovochich, M., Brant, J., Hotze, M., Sempf, J., Oberley, T., Sioutas, C., Yeh, J.I., Wiesner, M.R., Nel, A.E. (2006). Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Letters, 6(8): 1794-1807. doi: 10.1021/nl061025k.

Xia, T., Kovochich, M., Nel, A.E.  (2006). The role of reactive oxygen species and oxidative stress in mediating particulate matter injury. Clinics in Occupational and Environmental Medicine, 5(4): 817-836. doi: 10.1016/j.coem.2006.07.005.

Xia, G., Kovochich, M., Truitt, R., Johnson, B.D. (2004). Tracking ex vivo-expanded CD4+CD25+ and CD8+CD25+ regulatory T cells after infusion to prevent donor lymphocyte infusion-induced lethal acute graft-versus-host disease. Biology of Blood and Marrow Transplantation, 10(11): 748-760. doi: 10.1016/j.bbmt.2004.07.004.